Sharing the causes and improvement methods of loss of appetite caused by capmatinib (Touradida)

Capmatinib (Capmatinib), as a MET receptor tyrosine kinase inhibitor, is mainly used to treat patients with non-small cell lung cancer with MET exon 14 skipping mutations. During use, some patients may experience decreased appetite. This is mainly related to the fact that while the drug inhibits tumor growth, it has a certain impact on gastrointestinal nerves and metabolic regulation, leading to nausea, increased satiety, or decreased interest in food.

Decreased appetite may also be related to side effects from the medication, such as nausea, dry mouth, changes in taste, or mild fatigue. These symptoms will indirectly affect the patient's food intake, causing the body to consume insufficient energy and nutrients, further aggravating weight loss and fatigue. Such symptoms are more common during the initial treatment or dose adjustment phase, but most can be alleviated through intervention.

Methods to improve appetite loss include adjusting diet and eating patterns. It is recommended that patients eat small and frequent meals and choose high-calorie, high-protein, easy-to-digest foods. At the same time, they can try to increase the flavor and color of food to increase their interest in eating. When necessary, appropriate amounts of gastric motility drugs or nutritional supplements can be used under the guidance of a doctor to help relieve gastrointestinal discomfort and increase appetite.

In addition, psychological support and lifestyle adjustments are also important. Maintaining a good daily routine, exercising moderately, and relaxing can improve digestive function and appetite. At the same time, patients should regularly communicate with their attending doctors about their own conditions, monitor weight and nutritional indicators, and adjust drug dosage or provide nutritional intervention when necessary to ensure that the disease is controlled and good physical condition is maintained during the treatment process.

Reference materials:https://www.drugs.com/