Analysis of storage conditions and storage precautions for Capmatinib (Touradda)

Capmatinib is an oral small moleculeMET kinase inhibitor that is sensitive to environmental factors such as temperature and humidity. According to the drug instructions, capmatinib should be stored at room temperature around 25℃ (short-term fluctuations in the range of 15℃ ~ 30℃ are allowed) to avoid exposure to extreme high or low temperatures. During storage, medicines should be sealed and placed in their original packaging to prevent light and moisture in the air from affecting the stability of the medicines. Especially in areas with high temperatures in summer, it is not advisable to leave medicines in a car or on a window sill in direct sunlight for a long time to prevent the components of the medicines from being degraded by heat.

Capmatinib tablets are sensitive to humidity, so storage in humid environments such as bathrooms and kitchens should be avoided. After opening, it is not recommended to pour the tablets into other containers for mixing and storage. They should be kept in the original packaging of moisture-proof aluminum foil or bottles, and the bottle cap or aluminum bag should be closed tightly at all times to prevent moisture in the air from entering and causing the tablets to deteriorate. At the same time, medicines should be kept away from direct light and preferably stored in a cool, dry, light-proof medicine cabinet or drawer to prevent active ingredients from being decomposed by light and reducing their efficacy.

During daily medication, patients should avoid taking capmatinib tablets apart, crushing them, or exposing them to the air for too long, nor should they mix them with other drugs in a medicine box and carry them for a long time. If you need to go out or travel, it is recommended to use a well-sealed portable medicine box to ensure a dry, light-proof, normal temperature environment, and try to avoid long-term bumps, heat or humidity. If the travel time is long, the required doses can be packed in advance and stored in desiccant or moisture-proof bags to maintain the stability of the medicine.

The expiration date of capmatinib is usually clearly marked on the drug packaging. Patients should use it within the expiration date and should not continue to take expired drugs. Once the color, smell or appearance of the tablets changes, such as yellowing, powdering, moisture and clumping, etc., you should immediately stop using it and consult a pharmacist or doctor. Do not continue to take the medicine at your own discretion. Expired or spoiled capmatinib should be properly disposed of in accordance with local drug recycling or environmental protection disposal regulations. It should not be discarded or flushed into the sewer to prevent environmental pollution and the risk of accidental ingestion.

Reference materials:https://www.drugs.com/