What is the reason for weight loss (losing weight) or gaining weight (gaining weight) while taking trametinib?

Trametinib (Trametinib) may cause weight loss or gain for a number of reasons. Weight loss may be due to digestive side effects such as loss of appetite, nausea, and vomiting caused by the medication. On the other hand, weight gain may be related to drug-induced edema, muscle atrophy, or fat accumulation. In addition, trametinib may have metabolic effects that may lead to weight changes. However, specific weight changes may vary between individuals and may also be affected by other factors, such as eating habits, amount of exercise, lifestyle, etc. During treatment, it is important to monitor weight changes closely and report any unusual symptoms to your doctor. The doctor will evaluate the condition and adjust treatment as needed to ensure the patient's health and safety.