What fruits cannot be eaten while taking Trametinib?

It is best to avoid eating grapefruit (including grapefruit juice) and grapefruit while taking trametinib, as grapefruit contains certain chemicals that can affect the metabolism of the drug. The components in grapefruit may interfere with the drug metabolizing enzyme system in the body, causing the concentration of trametinib to increase in the body, thereby increasing the risk of adverse reactions or reducing the efficacy of trametinib. In addition, it is recommended to avoid eating too much fruits containing vitamin C while taking trametinib, because vitamin C may also affect the absorption and metabolism of the drug. In addition to grapefruit, generally speaking, other fruits are edible in moderate amounts. However, it is best to avoid eating too much fruit or fruits that affect drug metabolism under the advice of a doctor or pharmacist to ensure the efficacy and safety of trametinib. Regarding food choices, patients should follow the doctor's guidance and communicate with the medical team in a timely manner to obtain the most appropriate dietary advice.