What is the bioavailability of entrectinib?

Entrectinib(Entrectinib)is well absorbed when administered with an acidifier, and the absolute bioavailability is estimated to be>50%. After receiving a single radiolabeled dose of entrectinib, 83% of the radioactivity was present in the feces and 3% was present in the urine. Of the doses in feces, 36% were entrectinib and 22% were M5. The half-life of entrectinib is 20 hours. The half-life of the active metabolite M5 is 40 hours. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.