Is Dabrafenib a targeted therapy?

Dabrafenib and trametinib are targeted therapies. The principle of dabrafenib is to block BRAF, to prevent the growth and spread of cancer cells. Dabrafenib may reduce the effectiveness of hormonal contraceptives and an alternative method of contraception should be used. Concomitant use with strong inhibitors or inducers of CYP3A4 or CYP2C8 is not recommended. Drugs that increase gastric pH may decrease dabrafenib concentrations. Dabrafenib inhibits certain CYP isoenzymes; The concomitant use of drugs that are sensitive substrates of >CYP2C9, CYP2C19 or CYP2B6 may render these drugs ineffective. If you want to get more high-quality information, you can contact Yaode , Yaode will do its best to learn more about high-quality overseas drugs for you.