What is the mechanism of action of Dabrafenib?

Dabrafenib is a kinase inhibitor that inhibits some mutant forms of BRAFkinase, including BRAF V600E, BRAF V600K and BRAF The in vitro IC50 values of V600Denzyme are 0.65, 0.5 and 1.84 nM respectively. Dabrafenibis used alone or in combination with trametinib to treat melanoma(Skin cancer) that has spread or cannot be removed with surgery. It is also used with trametinib to help prevent melanoma from coming back after surgery. This method is used only if the melanoma cells have the BRAF V600E or V600K mutation. If you want to get more high-quality information, you can contact Yaode. Yade will do its best to learn more about high-quality overseas drugs for you.