Is genetic testing necessary to take larotrectinib?

Yes, genetic testing is usually required before treating patients with Larotrectinib. Larotrectinib is mainly used to treat malignant tumors carrying NTRK gene fusions. NTRKGene fusion is a rare but specific tumor mutation involving the nerve growth factor receptor (NTRK) gene. Genetic testing can help determine whether a patient carries the NTRK gene fusion and therefore whether he or she is a candidate for larotrectinib. This personalized treatment method can more accurately select patients and improve the effectiveness of treatment. Before starting treatment with larotrectinib, doctors often recommend genetic testing to make sure the drug is effective for the patient and that good results are expected.