How effective is larotrectinib in treating cancer?

Larotrectinib (Larotrectinib), as a targeted therapy, has shown significant efficacy in patients with tumors carrying NTRK gene fusions. NTRKGene fusion is a rare but specific tumor mutation involving the nerve growth factor receptor (NTRK) gene. Clinical trial results indicate that many patients with the NTRK gene fusion experienced durable treatment responses when treated with larotrectinib. The drug shows high specificity and effectiveness in such patients, and has also achieved good therapeutic effects on some advanced and refractory tumors. However, efficacy still varies among individual patients, so specific treatment effects need to be evaluated on a patient-by-patient basis. Patients should pay close attention to any symptoms of discomfort while using larotrectinib and receive regular monitoring and follow-up from their doctors to ensure the safety and effectiveness of the treatment.