How much does a box of Necitumumab cost?

Necitumumab is a recombinant human monoclonal IgG1 antibody targeting the epidermal growth factor (EGF) receptor. It is used as an EGFR antagonist for the treatment of non-small cell lung cancer (NSCLC). It works by binding to the epidermal growth factor receptor (EGFR) and preventing the binding of its ligand. The binding of nesituzumab to EGFR induces receptor internalization and degradation, thereby preventing further activation of EGFR, which is beneficial for non-small cell lung cancer because many patients have increased protein expression of EGFR. The German version of the generic version of Nexituzumab 800mg/50ml listed overseas may cost more than 10,000 yuan per box (the price may fluctuate due to exchange rates), which is relatively expensive.