Is Ruxolitinib effective?

Ruxolitinib tablets (Ruxolitinib) is a targeted cancer drug, which can also be called a cancer growth retardant. It can be used to treat certain myeloproliferative tumors, such as myelofibrosis and polycythemia vera. Before patients start treatment with ruxolitinib tablets, the doctor will recommend that the patient do a blood test to check for changes in the JAK2 gene. Ruxolitinib, the active ingredient in Ruxolitinib tablets, works by blocking a gene important in blood cell production called JAK2. Cancer growth blockers block growth factors that trigger cancer cells to divide and grow. Two trials of oral ruxolitinib tablets A phase III controlled myelofibrosis study showed significant benefit by reducing spleen size and alleviating debilitating symptoms.