Is Osimertinib effective for brain metastases?

Patients with non-small cell lung cancer may have cancer tissue metastasize to the brain, which is called brain metastasis. Osimertinib is generally effective, but it needs to be used under the guidance of a doctor. Osimertinib is mainly used to treat locally advanced or metastatic non-small cell lung cancer that is positive for the T790M mutation in the epidermal growth factor receptor. Studies have found that osimertinib achieves its therapeutic effect mainly by inhibiting protein synthesis in the epidermal growth factor receptor pathway of tumor cells. It has a certain effect in the treatment of brain metastasis and central nervous system metastasis, and has relatively few side effects.