Can Osimertinib be used in combination?

Osimertinib (Osimertinib) can be combined with other targeted drugs such as EGFR tyrosine kinase inhibitors and EGFR monoclonal antibodies, or MEK inhibitors and other drugs for treatment. Osimertinib is a cancer drug called a tyrosine kinase inhibitor that is used to treat non-small cell lung cancer with a specific mutation. When a gene mutation occurs, new genes appear in the body, which may cause resistance to osimertinib. After genetic testing, EGFR tyrosine kinase inhibitors that are sensitive to EGFR gene mutations can be used, such as dabrafenib, crizotinib, etc., which can be combined with osimertinib to produce new therapeutic effects. Osimertinib can also bind to EGFR on the surface of tumor cells and can effectively prevent tumor cell proliferation. For example, consider combining it with bevacizumab and other drugs for treatment.