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Will taking crizotinib cause cancer cells to metastasize?
Current clinical data do not show that crizotinib itself causes cancer cell metastasis. Crizotinib is a targeted drug mainly used to treat ALK fusion gene-positive non-small cell lung cancer (NSCLC) and ROS1 fusion gene-positive NSCLC. It blocks the proliferation and growth of tumor cells by inhibiting the activities of ALK and ROS1 protein kinases. But in some cases, due to the complexity and adaptability of tumor cells, some patients may develop drug resistance or disease progression during treatment. During the medication period, close monitoring of the condition and regular follow-up are the key to ensuring the therapeutic effect. When necessary, the doctor will adjust the treatment plan, such as switching to other targeted drugs or combination therapy.
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