Is crizotinib a targeted drug?

Yes, crizotinib is a targeted drug. It is a multi-target inhibitor, mainly targeting ALK (Anaplastic Lymphoma Kinase) protein kinase and ROS1 (c-ros oncogene 1) protein kinase, and also has a certain inhibitory effect on c-Met (hepatocyte growth factor receptor) protein kinase. Targeted drugs are a class of drugs that treat cancer by specifically inhibiting specific molecules or signaling pathways in tumor cells. Crizotinib has shown good efficacy in ALK and ROS1-positive non-small cell lung cancer (NSCLC).