Is Trastuzumab a targeted drug?
Trastuzumab (Trastuzumab) is a targeted prescription drug. It is a monoclonal antibody that blocks the growth and division of HER2-positive breast cancer cells by specifically binding to and inhibiting the function of human epidermal growth factor receptor 2 (HER2). This is a humanized IgG1 light chain monoclonal antibody in which the complementarity determining regions (CDRs) of a HER2-specific mouse monoclonal antibody are genetically engineered to link to the human antibody framework region. Trastuzumab has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of HER2-overexpressing breast cancer in the adjuvant and metastatic settings.
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