How does clofazimine treat drug-resistant tuberculosis?

Clofazimine (Clofazimine) plays an important role in the treatment of drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). As a secondary antimycobacterial drug, clofazimine is effective against strains that are resistant to traditional anti-tuberculosis drugs by inhibiting the cell membrane and protein synthesis of Mycobacterium tuberculosis. Often, clofazimine is given in combination with other anti-tuberculosis drugs to enhance efficacy and reduce the emergence of drug-resistant strains. Although clofazimine has obvious efficacy, its use still needs to be carried out under the guidance of a professional doctor, and the patient's liver and kidney function and skin reactions must be regularly monitored.