Can cycloserine be used in drug-resistant tuberculosis?

Cycloserine (Cycloserine) is a second-line anti-tuberculosis drug, mainly used in combination treatment regimens for multidrug-resistant tuberculosis and complicated tuberculosis infections. The drug works by inhibiting bacterial cell wall synthesis and has certain advantages in drug-resistant strains. It needs to be used in combination with other anti-tuberculosis drugs under the guidance of a doctor to prevent drug resistance and improve efficacy. At the same time, liver function and nervous system monitoring should be performed during treatment, because cycloserine may cause neuropsychiatric symptoms or peripheral neuritis, and early detection can alleviate the risk through dose adjustment. Patients should strictly abide by medical instructions during use and do not increase or decrease the dose on their own. They should also avoid concurrent use of drugs that may aggravate neurotoxicity to reduce the incidence of adverse events.