What should you pay attention to during trabectedin chemotherapy?

Trabectedin (Trabectedin) is an anti-cancer drug derived from the marine organism ascidian. It is commonly used to treat soft tissue sarcoma and recurrent ovarian cancer. The most important thing that patients need to pay attention to during use is changes in liver function, because the drug is mainly metabolized in the liver. ALT, AST and other indicators need to be tested regularly before and after treatment. If the values u200bu200bincrease, the doctor may delay or adjust the dose. In order to reduce adverse reactions, trabectedin is often combined with dexamethasone to reduce nausea, vomiting and liver burden. It is important to maintain adequate hydration on the day of medication to help with drug elimination and reduce fatigue. The course of trabectedin treatment is long, and reasonable monitoring and individualized dose adjustment are important links to ensure efficacy and safety.