Is cycloserine safe to treat drug-resistant tuberculosis?

Cycloserine (Cycloserine) is an antibiotic used in the treatment of drug-resistant tuberculosis. Because of its unique mechanism of action, it can inhibit bacterial cell wall synthesis, so it is often used in combination regimens. For patients, the safety issues of greatest concern are mainly related to the central nervous system, including the possibility of insomnia, anxiety, decreased concentration and even epileptic seizures. Doctors will pay special attention to the patient's past psychiatric history and epilepsy history when using cycloserine to avoid exacerbating the risk. During use, liver and kidney function and nervous system performance also need to be monitored regularly, and the dose should be adjusted or discontinued if necessary. Despite certain side effects, cycloserine remains one of the important options in the treatment of drug-resistant tuberculosis.