Will taking linezolid with food affect its efficacy?

The absorption of Linezolid (Linezolid) is less affected by food, but certain diets require special attention. High-fat foods may delay the time it takes for the drug to reach its peak, but it does not affect the overall absorption rate, so strict fasting is not necessary. However, patients need to avoid eating foods rich in tyramine (such as cured meats, fermented soy products), because linezolid has a weak monoamine oxidase inhibitor effect, and eating it together with tyramine may cause a hypertensive crisis. Alcohol also increases the risk of adverse effects on the central nervous system, such as dizziness or seizures. During treatment, it is recommended to maintain a light diet and consume more foods rich in vitamin K (such as spinach) to help maintain coagulation function.