How long does it take for Platinib to be effective in treating RET mutated lung cancer? Is the effect stable?

Pralsetinib (Pralsetinib) is a lung cancer treatment drug that targets the RET fusion gene. Many patients are concerned about how long it will take to see effects after using it. Generally speaking, some patients can see tumor shrinkage within 2-4 weeks after treatment. Early imaging examinations may show that the lesions are significantly reduced, and clinical symptoms such as cough and shortness of breath are gradually relieved. However, each patient's condition is different, and the time it takes for the drug to take effect may vary. Studies have shown that platinib has a higher objective response rate (ORR) in patients with RET fusion-positive lung cancer, and the response time of some patients can exceed one year, with good disease stability. However, attention still needs to be paid to the issue of drug resistance, as some patients may experience disease progression after a period of treatment.