Contraindications of anlotinib hydrochloride

Anlotinib hydrochloride is a drug used to treat a variety of cancers, but it may not work for all patients. Its contraindications mainly include the following aspects: First, patients who are allergic to any ingredients in anlotinib hydrochloride should avoid taking it to avoid the risk of allergic reactions. Secondly, because anlotinib hydrochloride is reproductively toxic, it is contraindicated in pregnant and lactating women to avoid potential harm to the fetus or infant. Additionally, patients with central squamous cell carcinoma of the lung or who are at risk for massive hemoptysis should be cautious as anlotinib hydrochloride may increase the risk of bleeding. In addition, for patients with hepatic and renal insufficiency, especially those with severe hepatic and renal insufficiency, anlotinib hydrochloride should be used with caution, because its metabolism and excretion may be affected, leading to accumulation of the drug in the body, which may increase the risk of adverse reactions. At the same time, patients with cardiac problems such as prolonged QT interval and torsade de pointes should be disabled to prevent further damage to cardiac function. The above information is for reference only. Before using anlotinib hydrochloride, patients should fully understand its contraindications and precautions, and use it under the guidance of a doctor.