What is the effect of osimertinib/osimertinib on brain metastasis?

Osimertinib/Osimertinib (Osimertinib) has shown certain effects in the treatment of brain metastases in patients with advanced non-small cell lung cancer (NSCLC). Brain metastasis is one of the common complications in patients with lung cancer, which has a great impact on the patient's survival rate and quality of life. BecauseOsimertinib/Osimertinib has high brain-blood-brain barrier penetration and strong targeting effect on EGFR mutations, so it has shown relatively good results in the treatment of brain metastases. Some studies have shown that Osimertinib/Osimertinib treatment of brain metastases in NSCLC patients can significantly reduce the size of the lesions, prolong the progression-free survival of the patients, and improve the overall survival. In addition, the targeting effect of osimertinib/osimertinib can reduce the toxic side effects on normal brain tissue, making it an effective option for the treatment of brain metastases. However, it is worth noting that the treatment of brain metastases usually requires a comprehensive consideration of multiple factors, such as the number and location of brain metastases, the patient's physical condition, and the condition before treatment. Therefore, the treatment plan should be comprehensively evaluated and formulated by a doctor based on individualized conditions.