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Cabozantinib functions and indications

Author: medicalhalo
Release time: 2026-02-01 22:25:32

Cabozantinib (Cabozantinib) is a multi-target tyrosine kinase inhibitor mainly used to treat various types of cancer. Its mechanism of action includes inhibiting multiple receptor tyrosine kinases (RTKs) such as MET, VEGFR, RET, KIT and AXL, etc., as well as the vascular endothelial growth factor (VEGF) signaling pathway. Through these effects, cabozantinib can inhibit the growth, spread and angiogenesis of tumor cells, thereby blocking tumor progression and metastasis. Cabozantinib is widely used to treat many types of cancer, especially advanced renal cell carcinoma, thyroid cancer, and hepatocellular carcinoma. In clinical practice, cabozantinib has been shown to have significant efficacy in improving patients' survival and quality of life, providing an important treatment option for patients with advanced cancer. However, patients need to closely follow their physician's recommendations and monitoring while using cabozantinib to ensure optimal treatment efficacy and safety.

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