What is the reason for weight loss (losing weight) or gaining weight (gaining weight) while taking dabrafenib?

Weight changes during dabrafenib treatment may be influenced by multiple factors. On the one hand, the drug itself may cause side effects such as loss of appetite, nausea, and vomiting, leading to weight loss. On the other hand, dabrafenib may affect the patient's metabolism or cause fluid retention, leading to weight gain. In addition, the cancer itself and the body's reactions related to treatment may also have an impact on weight. In short, weight changes may be one of the common reactions to dabrafenib treatment, but the specific reasons need to consider the patient's overall condition, eating habits, drug dosage and other factors, and be evaluated and managed by a doctor. Patients should regularly monitor weight changes during treatment and promptly inform the doctor of any discomfort or changes so that the doctor can adjust the treatment plan.