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The approved indication is to treat kidney transplant patients and prevent organ rejection in patients 13 years of age or older. Recommended for use in combination with cyclosporine and corticosteroids. As early as 1989, Morris officially began to study Rapamune (Sirolimus Tablets, Rapamune) as a new highly effective immunosuppressant for the anti-rejection effect of organ transplantation. The results showed that Rapamune (Sirolimus Tablets, Rapamune) has an effective anti-proliferative effect on peripheral blood mononuclear cells that is 50 to 500 times stronger than cyclosporine CA, but has lower nephrotoxicity than cyclosporine and tacrolix.

Rapamune (sirolimus tablets, Rapamune) is taken orally, once a day. It should be started as soon as possible after transplantation. For new transplant recipients, the loading dose that should be taken for the first time is three times the maintenance dose. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day.

In clinical trials, the loading dose of 15 mg and the maintenance dose of 5 mg/day were safe and effective, but for kidney transplant patients, the therapeutic benefits of doses above 2 mg are unclear. The overall safety profile of patients taking Rapamune (Sirolimus Tablets, Rapamune) 2 mg daily is better than that of patients taking Rapamune (Sirolimus Tablets, Rapamune) 5 mg daily.

Where can I buy Rapamin (sirolimus tablets)?

It is understood that it has been launched in China, and patients can purchase the drug at major domestic pharmacies with a prescription issued by a doctor. Rapamune (sirolimus tablets, Rapamune) produced by Biocon Pharmaceuticals in India is 1 mg x 10 tablets and sells for about $200. Due to factors such as exchange rate fluctuations, the price is not fixed. If patients want to know the specific price information of Rapamune (sirolimus tablets, Rapamune), or want to purchase the drug overseas, they can consult with domestic reliable overseas medical service institutions (such as Medical Companion Travel).

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