雷帕鸣西罗莫司片得吃多久才能有效果

Research on immunosuppressants has a long history. In terms of organ transplantation, the rejection of allogeneic organ transplants by the human body's own immune system has caused great trouble to the long-term survival of postoperative patients. Sirolimus (), formerly known as rapamycin. In 1989, Morris officially began to study this drug as a new and highly effective immunosuppressant for the anti-rejection effect of organ transplantation. The results showed that its effective anti-proliferative effect on peripheral blood mononuclear cells is 50 to 500 times stronger than that of cyclosporine CA, but its nephrotoxicity is lower than that of cyclosporine and tacrolix.

The effect of rapamycin sirolimus tablets combined with cyclosporine is more obvious. Currently, rapamycin combined with low-dose cyclosporine A is a better immunosuppressive treatment option after renal transplantation, and the use of rapamycin can reduce the dose of CNI. It is safe and effective to control the steady-state trough concentration of sirolimus at 4-8ng/ml or 5-8ng/ml after renal transplantation. Rapamin also reduces the incidence of non-melanoma skin cancer after kidney transplantation. In addition, rapamycin has also achieved good anti-rejection effects after heart transplantation, lung transplantation, corneal transplantation and other transplants, but the therapeutic concentration has not been reported.

The therapeutic effect of rapamin is very significant, and many patients will also ask: How long does it take to take rapamin and sirolimus tablets to be effective?

The specific onset time of (sirolimus) needs to be judged based on the patient's condition and own situation. Patients need to use the medication correctly and conduct relevant examinations during the treatment process. Because the safety and efficacy of rapamin have not been established in children under 13 years of age, its use is not recommended. If the patient has other special conditions, he or she needs to truthfully inform the doctor before taking the medication, and the doctor will adjust the medication according to the patient's own needs.

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