肾移植后西罗莫司片要吃多长时间?
How long should I take Rapamin after kidney transplantation? Let’s find out. Sirolimus tablets (rapamin) are mainly used in clinical practice to prevent and treat rejection reactions of kidney, liver and other transplants, and are especially suitable for patients with concurrent renal dysfunction, tremor, and hypertension. The drug, also known as sirolimus, can produce a synergistic effect when used in combination with cyclosporine, which is better than either of them alone, and better than the combination of sirolimus tablets (rapamin) plus mycophenolate mofetil or cyclosporine plus mycophenolate mofetil.
The immunosuppressive mechanism of sirolimus tablets (rapamin) is completely different from other currently used immunosuppressants. It has low toxicity and basically no nephrotoxicity. It can be combined with low-dose tacrolimus, cyclosporine, mycophenolate mofetil or hormones to form different dual immunosuppressive regimens. Patient t can obtain satisfactory results by insisting on taking rapamycin, and its efficacy and role have also been confirmed by clinical experiments.
However, in order to maximize the benefit from it, patients need to master the correct medication method. The specific daily dosage of sirolimus tablets (rapamin) is: Sirolimus tablets (rapamin) are recommended to be used in combination with cyclosporine and corticosteroids. The medication is taken orally once a day. Patients should start taking it as soon as possible after receiving a kidney transplant. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. As for how long to take sirolimus tablets (rapamin), it still depends on the patient's personal recovery. Although the loading dose of 15 mg and the maintenance dose of 5 mg/day used in clinical trials are safe and effective, the therapeutic benefits of doses above 2 mg are unclear for kidney transplant patients. The overall safety profile of patients taking 2 mg of rapamide daily was better than that of patients taking 5 mg rapamide daily.
Sirolimus tablets (Repamin) are currently on the market in China. Patients can contact some professional and reliable overseas medical service organizations in China (such as Medical Companion Travel) to obtain more cost-effective (Repamin).
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