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Introduction: Sparsentan is the only oral, once-daily, non-immunosuppressive drug that directly targets glomerular damage in the kidneys by blocking two key pathways for IgAN disease progression (endothelin-1 and angiotensin II), significantly slowing renal function decline within two years.

Where to buy Sparsentine more reliably

The most reliable ways to buy Sparsentine are as follows.

1. Hospital pharmacies: Patients can go to local general hospitals or specialized hospitals in the countries where Sparsentan is listed, and purchase it directly in the hospital pharmacies after the doctor issues a prescription.

2. Online pharmacies: Some regular online pharmacies may provide spaxentan purchase services. You can find more online pharmacies for consultation and purchase.

3. Physical pharmacies: Patients can also purchase Sparsentan in regular local pharmacies in the countries where Sparsentan is listed. A medical prescription is usually required before purchase.

4. Medical service institutions: Since Sparsentan has not yet been launched in China, patients can also consider purchasing it through formal overseas medical service institutions. After purchasing the drug, they can obtain the drug through direct mail.

5. Participate in clinical trials: If sparsentan is undergoing relevant clinical trials in China, patients may consider joining. This will not only provide free treatment opportunities, but also provide important data support for the launch of the drug in China.

Since spaxentan is a prescription drug, patients must obtain a doctor's prescription and understand the price, etc. before purchasing or using it.

Sparsentan Medication Precautions

1. Hypotension: For patients at risk of hypotension, consider discontinuing sparsentan or adjusting other antihypertensive drugs and maintaining appropriate volume status. If hypotension occurs despite discontinuation or reduction of other antihypertensive agents, consider reducing or interrupting the sparsentane dose. Transient hypotensive reactions are not a contraindication to continuing to take sparsentan, which can be administered once blood pressure has stabilized.

2. Acute kidney injury: Monitor renal function regularly, and consider discontinuing treatment for patients who experience clinically significant decline in renal function while taking sparsentane.

3. Hyperkalemia: Monitor serum potassium regularly and provide appropriate treatment. Patients with end-stage renal disease, taking potassium-increasing drugs (such as potassium supplements, potassium-sparing diuretics), or using potassium-containing salt substitutes are at increased risk of developing hyperkalemia and may need to reduce the dose or discontinue sparsentan.

4. Fluid retention: Sparsentane can cause fluid retention, manifested as edema. If clinically significant fluid retention occurs, the patient needs to be evaluated to determine the cause and whether diuretic therapy may need to be initiated or adjusted. The dose of sparsentane should then be considered.

The price of Sparsentine

The price of Sparsentine varies according to different versions and purchase channels. The price of the Hong Kong version of Sparsentine is about 7830$-8300$ per box, and the price of the American version of Sparsentine is about 111510$-111800$ per box.

The above prices are for reference only. These drug prices may be affected by factors such as market supply, regional differences, sales channels, and exchange rates, and the prices are not fixed. When purchasing, it is recommended to obtain the most accurate price information through formal channels and consulting professional medical service agencies.