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Rufinamide is a new type of triazole derivative anti-epileptic drug developed by Japan's Eisai Company. It has a unique mechanism of action. It effectively reduces abnormal neuron discharge by regulating the activity of voltage-gated sodium ion channels in the brain, providing a new strategy for the treatment of epilepsy. This article will provide practical information from three aspects: reliable purchasing channels, global listing status, and price reference. At present, the drug has been approved for marketing in many European and American countries, but you still need to choose formal channels when purchasing to avoid fake and shoddy products.

Where to buy rufinamide more reliably

Selecting formal and reliable purchasing channels is the key to ensuring the quality of drugs. Patients should choose officially recognized drug purchasing channels according to the drug regulatory policies of their region.

Hospital specialty pharmacies

In countries where it has been approved for marketing, neurology departments in large tertiary hospitals are usually equipped with rufinamide. Patients need to purchase the medicines with a prescription from a specialist, and the medicines are dispensed directly from the hospital pharmacy. Hospital channels can provide professional medication guidance and follow-up monitoring services.

Authorized chain pharmacies

Some countries allow authorized pharmacies to sell anti-epileptic drugs. Patients can check the list of authorized pharmacies through the national drug regulatory website. When purchasing, they need to check the drug batch number, expiration date and anti-counterfeiting label. It is recommended to choose a chain institution with professional neurological pharmacy qualifications.

You need to be particularly cautious when purchasing drugs across borders. It is recommended to go through the international medical department of the hospital or a regular drug import agent, and keep complete drug purchase vouchers and logistics records for inspection.

The marketing status of rufinamide

Understanding the approval status of rufinamide in various regions around the world will help patients choose legal ways to purchase the drug. The drug's marketing process shows obvious regional differences.

Main market approval process

It was approved for marketing by the European Medicines Agency (EMA) in January 2007 and certified by the US FDA in November 2008. Its indications are auxiliary treatment of epileptic seizures related to Lennox-Gastaut syndrome in children 1 year old and above and adults. Japan approved it in 2010 under the trade name Inovelon.

Special access channel

Patients in unlisted regions can apply for use through the designated patient import procedure. This procedure requires complete medical records and a special application to the drug regulatory department through the hospital. The entire process usually takes 2-4 weeks for approval.

Patients can check the latest approval information through the official websites of each country’s food and drug administration, or consult the attending physician to learn about the specific policies in their region.

The price of rufinamide

Drug prices are affected by multiple factors such as patent status, regional policies and procurement channels. Understanding international market prices can help patients make a budget for treatment.

Original drug price reference

The original drug produced by Japan Eisai Company is priced at approximately US$112 for 100mg*100 tablets and US$166 for 200mg*100 tablets. The price of products with the same specifications in the U.S. market has increased by 15%-20% due to higher distribution costs.

Price range of generic drugs

The 100mg specification of Indian generic drugs is about 40%-60% of the original drug. Some Middle Eastern countries can obtain 60%-70% of the price of the original drug through centralized government procurement. Special attention should be paid to bioequivalence certification when purchasing generic drugs.

Drug prices will change with purchase volume and exchange rate fluctuations. Patients taking medications for a long time may consider joining pharmaceutical company assistance programs to reduce their financial burden.