苯巴那酯治疗癫痫的效果好吗？吃多久有效果？

Cenobamate is a prescription drug used to treat partial-onset epilepsy in adults. It is not known whether it is safe and effective in children. Cenobamate can reduce repetitive neuronal discharges by inhibiting voltage-gated sodium currents. It is also a positive allosteric modulator of gamma-aminobutyric acid (GABA A) ion channels. Is it effective in treating epilepsy? How long does it take to have an effect?

A multicenter, double-blind, randomized, placebo-controlled trial confirms that cenobamate is an effective treatment option for adults with focal-onset epilepsy uncontrolled on 1 to 3 antiepileptic drugs (ASMs).

During the 12-week maintenance period, all doses of cenobamate demonstrated significantly higher response rates compared with placebo. The response rates of the 100 mg/day, 200 mg/day, and 400 mg/day groups were 40%, 56%, and 64% respectively, while the placebo group was 25%.

In addition, during the maintenance period, 4%, 11%, and 21% of patients treated with 100 mg, 200 mg, and 400 mg cenobamate, respectively, experienced a 100% reduction in seizure frequency (100% seizure-free), compared with 1% in the placebo group. From the above experimental data, it can be seen that the therapeutic effect of cenobamate is very good. The successful development of this drug has brought new treatment options to many epilepsy patients.

Because each patient's condition, personal constitution, and tolerance to drugs are different, the effective time and therapeutic effect after receiving cenobamate treatment will also be different. The effective time after treatment with cenobamate is mainly determined by the patient's own condition, and there is no accurate time point. Patients should strictly follow the doctor's diagnosis and treatment recommendations when receiving drug treatment, and I believe they will have good results soon.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

Recommended hot articles: