氨己烯酸片的作用和功效，氨己烯酸一次吃几片？

Vigabatrin tablets (Vigabatrin) are analogs of γ-aminobutyric acid (GABA). They can specifically bind to GABA aminotransferase and irreversibly, leading to an increase in the concentration of GABA in the brain, thereby exerting anti-epileptic effects. This product is used as adjuvant therapy for the treatment of patients who are ineffective with other anti-epileptic drugs, especially those with partial seizures (mainly used to control complex partial seizures). Vigabatrin tablets (vigabatrin) can aggravate absence seizures or myoclonic seizures. (Vigabatrin) may also be used in infants with West syndrome (infantile spasms), which is generally unresponsive to conventional antiepileptic drugs. As an auxiliary therapeutic drug, this product can achieve better efficacy. When used alone, it is effective in the treatment of newly diagnosed patients.

46 patients with infantile spasms who were diagnosed and treated from April 2015 to September 2016 were selected to be treated with oral vigabatrin. The starting dose was 50 mg/(kg. d) and increased to 100 mg/(kg. d) on the second day. If the symptoms were obviously controlled, the application was continued for 3 to 6 months and the electroencephalogram was reviewed regularly. If it was ineffective after 1 week, the dose was increased to 150 mg/(kg. d). , application is 3 to 6 months, and follow-up time is 3 to 10 months. Results: The total effective rate of azibazoline monotherapy was 67.4% (31/46), the seizure-free rate was 19.6% (9146), and the recurrence rate was 6.5% (3/46). The main short-term adverse reactions were lethargy, anorexia, irritability, and hyperactivity. Conclusion: Vigabatrin has a significant effect in treating infantile spasms, with a low recurrence rate. Adverse reactions usually appear in the early stages. The therapeutic effect of vigabatrin tablets is very excellent.

How many tablets of vigabatrin should be taken at one time? The recommended dose for adults is 3g per day, taken in divided doses. The dose should be increased according to the clinical effect at a rate of 0.5-1g per day to 4g per day (or 50mg/kg per day), which is effective for complex partial seizures of epilepsy (with or without generalized tonic-clonic seizures). General usage for children: For children aged 3-9 years, the recommended dose is 1g per day, divided into 2 times; for older children, 2g per day, divided into 2 times.

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