赛诺菲的喜保宁对婴儿痉挛症有用吗?
Regarding the clinical application indications of Vigabatrin (vigabatrin tablets), it is usually used for partial seizures of epilepsy, and can also be used in combination with other anti-epileptic drugs to treat refractory epilepsy. It can also be used for children with Lennox-Gastaut syndrome and West syndrome (infant pain syndrome). It is not effective for epileptic seizures and muscle spasms.
Forty-six patients with infantile spasms who were diagnosed and treated at Severance Children's Hospital in South Korea from April 2015 to September 2016 were treated with oral vigabatrin. The starting dose was 50 mg/(kg·d), and was increased to 100 mg/(kg·d) on the second day. If the symptoms were obviously controlled, the application was continued for 3 to 6 months, and the electroencephalogram was reviewed regularly; if it was ineffective after 1 week, the dose was increased to 150 mg/(kg·d). d), application for 3 to 6 months, follow-up time of 3 to 10 months.
Results: The total effective rate of vigabatrin monotherapy was 67.4% (31/46), the seizure-free rate was 19.6% (9/46), and the recurrence rate was 6.5% (3/46). The main short-term adverse reactions were lethargy, anorexia, irritability, and hyperactivity. Conclusion: Vigabatrin is effective in treating infantile spasms with low recurrence rate and adverse reactions usually appear early.
Currently on the market more patients are keen on Sanofi's. Sanofi (NYSE: SNY) was founded in 1973. Its predecessor was Sanofi-Aventis. It was changed to its current name: Sanofi in May 2011. It is headquartered in Paris, France, and has 113,496 full-time employees in more than 100 countries around the world. It is the world's leading diversified pharmaceutical and health company with diversified products, including drugs, vaccines and innovative treatment solutions. According to Medical Companion Travel, the specification of Sanofi Vigabatrin is 500mg*100 capsules/box, and the price is equivalent to RMB 1,450. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about Vigabatrin, please contact Medical Companion Travel for details.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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