法国赛诺菲氨己烯酸怎么使用？

Tablets are used as adjuvant therapy for the treatment of patients who are refractory to other anti-epileptic drugs, especially those with partial seizures (mainly used to control complex partial seizures). This product may aggravate absence seizures or myoclonic seizures. Today we will learn more about how to use vigabatrin from Sanofi France?

Recommended dosage of vigabatrin tablets: 3 g orally per day (1.5 g twice per day). The 6 g/day dose did not show additional benefit compared with the 3 g/day dose and was associated with an increased incidence of adverse events. Patients should not increase their dosage without authorization.

The usual adult dosage of vigabatrin tablets for the prevention of epileptic seizures is as follows: Initial dose: 1 g per day (containing 500 mg orally twice a day with or without food), the total daily dose may be increased by 500 mg weekly, depending on response.

Usual pediatric dosage for epilepsy: Infantile spasms: 1 month to 2 years: Initial dose: 50 mg/kg/day of vigabatrin tablets oral solution in two divided doses, with or without food. The dose may be increased in increments of 25 to 50 mg/kg/day every 3 days, up to a maximum of 150 mg/kg/day. Vigabatrin tablets should be administered under the guidance of an epilepsy specialist or child neurologist. Reactions after taking the medication should be reported to the doctor promptly.

Vigabatrin tablets are the drug of choice for TSC epilepsy in foreign countries. In terms of controlling Tsc epileptic seizures, about 95% of children have a good response to vigabatrin tablets. Once a seizure is discovered, regardless of form, vigabatrin tablets can be the first choice, and the effect is better when used for the first time. Especially for infantile spasms (peak arrhythmia in electroencephalogram), vigabatrin tablets should be taken as soon as possible.

Vigabatrin tablets may also be used in infants with West syndrome (infantile spasms), which is generally unresponsive to conventional antiepileptic drugs. As an auxiliary therapeutic drug, vigabatrin tablets can achieve better efficacy. When used alone, it is effective in the treatment of newly diagnosed patients.

The above is the usage method, I hope it can help you!