氨己烯酸片(喜保宁)的适应症

(Vigabatrin) is the first-choice drug for TSC epilepsy in foreign countries. In terms of controlling TSC epileptic seizures, about 95% of children have a good response to vigabatrin tablets. Once a seizure is discovered, regardless of form, vigabatrin tablets can be the first choice, and the effect is better when used for the first time. Especially for infantile spasms (peak arrhythmia in electroencephalogram), vigabatrin tablets should be taken as soon as possible.

The use of vigabatrin tablets (Vigabatrin) should be carried out under the guidance of an epilepsy expert or a child neurologist. Reactions after taking the medication should be reported to the doctor promptly. Vigabatrin tablets (Vigabatrin) are oral medicines that can be taken once or twice a day, before or after meals. It is advisable to drink half a glass of water when taking the medicine.

If your epilepsy does not improve after taking it for a sufficient period of time, you should stop taking Vigabatrin. At this time, Vigabatrin should be gradually discontinued under the supervision of a doctor.

Vigabatrin tablets (Vigabatrin) have good effects, but there will be side effects after long-term use. The side effects of the drug are basically inevitable during the treatment period. Common side effects of Vigabatrin tablets (Vigabatrin) include fatigue, drowsiness, headache, dizziness, confusion and depression. Occasional aggressive behavior and psychosis (more common in patients with a history of psychosis and behavioral problems), memory loss, diplopia, weight gain, gastrointestinal disturbances, edema, and alopecia. Nystagmus, nervousness, agitation, ataxia, paresthesia, and tremor may also occur.

After patients took vigabatrin tablets (Vigabatrin), the incidence of visual field defects was very high (about one-third). This often occurs after several months to several years of using Vigabatrin.

Visual field defects can be severe, which can have real consequences for the patient. Most patients with visual field loss have no obvious symptoms. Therefore, this adverse effect can only be confirmed through systemic examination, which is often only possible in patients over 9 years of age. In this regard, a method based on field-specific visual evoked potentials was specially developed to detect visual impairment in children aged 3 years and above. This method can be obtained from the Vigabatrin Tablets (Vigabatrin) company. However, so far, this method has not been legally verified to detect visual field defects caused by taking (Vigabatrin). Electroretinography is an effective method of testing for visual field defects, but it is only suitable for adults or very young infants who cannot perform visual field testing.

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