Agamree一次能囤几盒?多少钱?

Agamree (vamorolone) reduces the side effects of traditional steroids while maintaining anti-inflammatory effects by binding to the glucocorticoid receptor and modulating its downstream activity. The drug was approved by the U.S. Food and Drug Administration (FDA) on October 26, 2023, for DMD patients aged 2 years and above, and was subsequently approved in the European Union, the United Kingdom, Germany and other regions. This article will introduce in detail the purchase restrictions, pricing system and medication precautions for special groups of this drug, and provide patients with comprehensive medication guidance.

How many boxes can Agamree stock at a time

The purchase quantity is limited by the characteristics of the drug and regulations. Reasonable planning of the purchase amount is crucial for continued treatment.

Standard purchase restrictions

In regions where marketing is approved, prescriptions are usually limited to 1-2 boxes/time, and the total amount does not exceed 30 days' supply. This restriction is based on drug stability and safe medication considerations.

Special reserve plan

For patients in remote areas, doctors can apply for a special 3-month dosage approval and must provide a detailed medication management plan and follow-up arrangements.

Cross-border purchase restrictions

When importing through licensed channels, Chinese customs allows entry of up to 3 months’ worth of medicines, and original prescriptions and diagnostic certificates are required.

Properly planning the quantity of medicines purchased can not only ensure continuous treatment, but also avoid the waste of expired medicines.

How much does Agamree cost?

The pricing of Agamree reflects its value as an innovative drug for rare diseases, and the global price system is relatively unified.

Basic pricing

The price of Agamree produced by Swiss pharmaceutical company Santhera Pharmaceuticals is approximately US$9,764 per box, which includes the cost of drug development and ongoing safety monitoring.

Regional price differences

Some countries in the EU have obtained discounts through medical insurance negotiations, while prices in the US market are basically the same, but additional pharmacy service fees need to be paid.

Long-term treatment cost

Based on standard dosage, the annual treatment cost is approximately US$117,000. Pharmaceutical companies provide up to 70% cost reduction for eligible patients.

Understanding the complete price system can help patient families evaluate the burden of treatment and formulate reasonable financial plans.

Agamree medication for special groups

The use of Agamree by specific groups requires adjustment of the plan, and it is recommended to use the medication under the guidance of a doctor.

Pediatric patients

Children under 6 years old need to strictly monitor their growth and development indicators. It is recommended that the starting dose be adjusted according to body weight and the medication regimen should be evaluated every 4 weeks.

Patients with hepatic insufficiency

Patients with moderate liver impairment need to reduce the dose by 30%. Patients with severe liver disease are contraindicated. ALT and AST levels should be monitored monthly during treatment.

Elderly patients

Patients over 65 years old need to strengthen bone density monitoring. It is recommended to supplement calcium and vitamin D simultaneously, and increase the frequency of blood pressure monitoring to once a week.

Pregnant women

Use only when clearly needed, and the dosage needs to be gradually reduced after the second trimester. Not recommended for use during lactation, as the drug can be excreted in breast milk.

Developing individualized plans for special groups can maximize the efficacy while reducing risks.