地夫可特(Deflazacort)导致的不良反应怎么治疗？

Introduction: Deflazacort is a corticosteroid that works in the body to reduce inflammation and suppress the immune system. It's unclear how deflazacort helps people with Duchenne muscular dystrophy (DMD), but the drug can help improve muscle strength and slow symptoms from getting worse.

Adverse reactions caused by Deflazacort

It is commonly used to treat Duchenne muscular dystrophy and other autoimmune diseases, and may also cause some adverse reactions during medication.

1. Common side effects: Mainly include Cushingoid appearance, weight gain, increased appetite, upper respiratory tract infection, cough, frequent urination, nose or throat infection, excessive hair growth, irritability, runny nose, and stomach discomfort.

2. Serious side effects: severe skin reactions, including rash, fever, skin blistering and peeling, severe allergic reactions, including urticaria, difficulty breathing, difficulty swallowing, swelling of the face, lips, tongue or throat, etc.

3. Other side effects: also include nausea, thirst, infection, abnormal heart rate, pain, dizziness, mood and behavioral changes, hot flashes, etc.

The occurrence of side effects is related to individual differences, and not all patients will experience the above side effects. Follow your doctor's instructions while using deflazacort and have regular physical exams to monitor for potential side effects.

How to treat the adverse reactions of Deflazacort

1. Changes in endocrine function: Long-term use of Deflazacort may lead to hypothalamic-pituitary-adrenal axis suppression, Cushing's syndrome and hyperglycemia. Patients need to monitor these conditions regularly.

2. Immunosuppression and increased risk of infection: It is necessary to closely monitor the signs and symptoms of infection and seek medical treatment promptly when infection occurs.

3. Behavioral and emotional disturbances: If these symptoms occur, you should seek medical treatment promptly and consider whether the dosage of the medication needs to be adjusted or the medication changed.

4. Skin rash: When signs of rash appear for the first time, use should be terminated unless the rash clears up and is not related to the drug.

If side effects occur, you should contact your doctor immediately and follow the doctor's advice. Your doctor may recommend adjusting your dosage, changing medications, or taking other treatments.

Precautions for taking Deflazacort

1. Deflazacort can be taken with food or alone. Do not take deflazacort with grapefruit juice as this combination may increase the concentration of the drug in your body, causing more side effects.

2. If you take deflazacort tablets, you can swallow them whole, or you can crush the tablets and mix them with applesauce. Once mixed with applesauce, it should be consumed immediately.

3. If you take deflazacort suspension, be sure to shake the bottle well. Only use the measuring device provided with the suspension to ensure the correct dose is given. Do not use household measuring spoons or cups as this may result in measuring the wrong dose.

4. One month after opening deflazacort, please discard all unused deflazacort suspension.