valcyte的效果好吗?
Is the treatment effective? Let us take a look below. Valcyte is an antiviral drug produced by the Swiss company Roche. It is used to treat patients with acquired immunodeficiency syndrome (AIDS) combined with cytomegalovirus (CMV) retinitis, and to prevent CMV infection in high-risk solid organ transplant patients.
Valcyte tablets are sensitive to human viruses including human cytomegalovirus (HCMV), and valcyte tablets are sensitive to herpes simplex virus-1 and herpes simplex virus-2 (HSV-1, HSV-2), human herpesvirus-6, 7, 8 (HHV-6, 7, 8), Epstein-Barr virus, varicella-zoster virus (VZV) and hepatitis B virus. What is the therapeutic effect of valcyte tablets? This is an issue that patients are more concerned about.
Clinical studies of valcyte tablets in AIDS patients infected with CMV retinitis have shown that valcyte tablets and intravenous valcyte are equally effective in the induction treatment of CMV retinitis. In the study, patients with newly diagnosed CMV retinitis were randomly assigned to the valcyte group or the intravenous valcyte group for induction therapy. The proportion of patients with progression of CMV retinitis at week 4 was the same in both groups. After induction therapy, both groups of patients in the study continued to receive maintenance therapy with 900 mg of valcyte tablets per day. Among patients who received valcyte tablets or intravenous valcyte induction therapy followed by maintenance treatment with valcyte tablets, the mean (median) time from randomization to progression of CMV retinitis was: 226 (160) days and 219 (125) days.
The antiviral effect of valcyte tablets has been clinically demonstrated in the treatment of AIDS patients with newly diagnosed retinitis (clinical study WV15376). The detection rate of CMV virus decreased from 46% (32/69) to 7% (4/55) after 4 weeks of treatment with valcyte tablets, and the U.S. Food and Drug Administration (FDA) approved the increased use of valcyte tablets in adult kidney transplant patients at high risk for cytomegalovirus (CMV) disease. The above is about the treatment effect. If you have other questions, please consult the medical companion travel service.
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