注射安进狄诺塞麦的注意事项

Is a human monoclonal antibody, RANKL inhibitor, indicated for the treatment of osteoporosis, therapy-induced bone loss, metastasis to bone, and giant cell tumor of bone. Works by preventing the development of osteoclasts, cells that break down bone (bone resorption). Denosumab, developed by biotech company Amgen, reduces the risk of fractures in cancer patients. Amgen was founded in 1980 by a group of scientists and venture capitalists. Amgen is principally engaged in the discovery, development, production and sales of innovative drugs for human use, and is committed to exploring the potential of biotechnology for the treatment of patients with serious diseases. By leveraging cutting-edge human genetics and other tools, Amgen seeks to unravel the complexity of disease and lay the foundation for understanding human biology.

Each drug has some precautions to protect patients during the treatment process. Precautions for injecting Amgen denosumab: (1) Do not use the same active drug: patients taking denosumab should not use denosumab. (2) Allergic reactions may occur when using denosumab; if an allergic reaction occurs, the medication should be discontinued permanently. (3) Hypocalcemia: Denosumab may cause severe symptoms of hypocalcemia, or be fatal. Hypocalcemia should be corrected before medication, and the patient's blood calcium level should be monitored during treatment, especially in the first week of first medication, and calcium and vitamin D should be supplemented appropriately. (4) Osteonecrosis of the jaw (ONJ): Osteonecrosis of the jaw (ONJ) ​​has been reported. Oral examination should be performed before medication, symptoms should be observed during treatment, and any invasive dental procedures should be avoided. (5) Atypical femoral fracture: Assess the patient’s thigh or groin pain to diagnose atypical femoral fracture. (6) Hypercalcemia after discontinuation of medication: Monitor patient’s symptoms and treat appropriately. (7) Embryo-fetal toxicity: It harms the fetus. Women of childbearing age should be informed of the dangers of this drug and take effective contraceptive measures.

Recommended related hot articles: /newsDetail/93097.html