美国安进地舒单抗注射液的效果怎么样
It has outstanding clinical advantages over zoledronic acid treatment, that is, the occurrence time of SRE is significantly prolonged, and as a new model, denosumab is easy to use. It is injected subcutaneously every month, does not require intravenous infusion, does not require monitoring of renal function, and does not require the first-pass effect caused by intravenous infusion of zoledronic acid. It is a new drug suitable for the treatment of bone metastases in various tumor types. Desosumab can prevent the interaction of RANKL and its receptor, thereby inhibiting the formation, survival and function of osteoclasts, reducing bone resorption and increasing bone density. In May 2010, the drug was approved by the European Union for the treatment of postmenopausal osteoporosis and hormone suppression-related bone loss in prostate cancer patients. It is a promising new method for the treatment of osteolytic bone metastases.
The latest analysis of the study, presented at the European Society for Medical Oncology (ESMO) Annual Meeting in 2017, showed that among patients who could be surgically resected, 80% improved with neoadjuvant denosumab: 44% underwent surgery with less functional impact and 37% avoided surgery. In unresectable patients, denosumab resulted in effective long-term disease control with a 5-year progression-free survival (PFS) rate of 88%.
As one of the world's largest biopharmaceutical companies, Amgen is a leader in the global biopharmaceutical industry. It has strong R&D capabilities and product advantages. It insists on developing in the field of biotechnology for disease treatment. Its main fields include human genome, cancer, neuroscience and small molecule chemistry. According to Medical Travel, the current specification of Amgen in the United States is 120 mg, and the price is only $1,450, which is more suitable for patients to use for a long time. Since the exchange rate has been fluctuating for a long time and the price is unstable, please contact Medical Travel for details.
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