狄诺塞麦国内有售吗？

Prior to the approval of denosumab, no drug had been approved for the treatment of giant cell tumor of bone. For patients with resectable giant cell tumors of bone, the primary treatment option is surgery. The emergence of denosumab (denosumab) broke this deadlock.

Denosumab (denosumab) is the first approved monoclonal antibody that specifically targets RANK ligand. RANK ligand is a transmembrane or soluble protein that is necessary for osteoclasts to maintain their structure, function, and survival. Human RANKL mRNA is mainly found in bones, bone marrow and lymphoid tissues. Its main function in bones is to stimulate the differentiation and activity of osteoclasts and inhibit the apoptosis of osteoclasts. Osteoclasts are responsible for bone resorption, and osteoclast precursors must have low levels of macrophage colony-stimulating factor and RANKL during their differentiation into mature osteoclasts. Denosumab (denosumab) promotes bone remodeling and reduces the incidence of vertebral, nonvertebral, and hip fractures in postmenopausal women with osteoporosis.

So is denosumab (denosumab) available in China?

Because denosumab (denosumab) is a new drug from abroad, it has not been sold in China for the time being after its approval. Fortunately, denosumab (denosumab) produced by the American company Amgen has been launched in Turkey, and the price is the lowest in the world. The specification of Turkish denosumab (denosumab) is 120 mg, and the price is equivalent to RMB 1,500.

How to purchase the original drug denosumab (denosumab) sold in Turkey by Amgen of the United States:

1. You can go to Turkey to buy it in person, but this is more time-consuming and labor-intensive. The most important thing is that the Turkish denosumab (denosumab) market is difficult to distinguish between genuine and fake, and it is extremely easy to be deceived.

2. Find overseas medical service agencies in China (such as Medical Companion Travel), who will translate the cases, contact experienced doctors in Turkish hospitals to write prescriptions, and deliver the medicines to patients via direct mail from Turkish pharmaceutical factories. They will also guide and answer questions for patients while taking (denosumab). This is currently the most convenient and fastest solution.

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