唑来膦酸的作用和功效用途

唑来膦酸（Zoledronic Acid）是抗肿瘤辅助用药，是白色的或类白色的粉末，唑来膦酸需要用氯化钠注射液或葡萄糖注射液来稀释。 What are its functions and uses?

Zoledronic acid functions and uses

The main pharmacological effect of Zoledronic Acid is to inhibit bone resorption. The mechanism of action of Zoledronic Acid is not fully understood and may be related to multiple effects. Zoledronic acid can inhibit osteoclast activity and induce osteoclast apoptosis in vitro. It can also block the resorption of mineralized bone and cartilage by osteoclasts by binding to bone. Zoledronic acid can also inhibit the increase in osteoclast activity and the release of bone calcium induced by a variety of stimulating factors produced by tumors.

The main function of Zoledronic Acid is to inhibit bone resorption. Clinically, Zoledronic Acid is mainly used to treat bone pain caused by osteolytic bone metastasis of malignant tumors. Applied once a month, with each infusion lasting no less than 15 minutes, it can effectively treat bone metastases.

综合两项试验数据显示：接受治疗2个月后，唑来膦酸（Zoledronic Acid）显示出显著优于利塞膦酸钠的治疗效果，176例病人中有158例达到治疗显效标准。 SAP normalization rate was 63%, compared with 47% and 26% in the risedronate treatment group. 6个月后，唑来膦酸（Zoledronic Acid）组的176例病人中有169例达到治疗显效标准（96%），有89%的患者SAP水平恢复正常，而利塞膦酸钠组的171例患者仅有127例达到治疗显效标准。 According to clinical trial data, the therapeutic effect of Zoledronic Acid is very significant.

以上就是关于唑来膦酸（Zoledronic Acid）的介绍，患者如果想要了解更多关于该药品的药品资讯，可以向医伴旅客服咨询。

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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