布地奈德可以长期用吗

Can budesonide be used long-term? Budesonide is a glucocorticoid, and long-term use may cause a decline in the body's immunity. Therefore, long-term use is not recommended, and patients need to use budesonide under the guidance of a doctor.

Budesonide is an anti-inflammatory corticosteroid with high glucocorticoid effects and weak mineralocorticoid effects. The affinity of budesonide for the glucocorticoid receptor reflects the intrinsic potency of the drug, which is 200 times that of cortisol and 15 times that of cortisol. Budesonide is a glucocorticoid with highly potent local anti-inflammatory effects.

Budesonide Dosage: Take once daily in the morning. Swallow the capsule whole. Do not chew or crush. For patients who are unable to swallow the entire capsule, open the capsule and pour the granules into a tablespoon of applesauce. Mix and consume entire contents within 30 minutes. Do not chew or crush. Follow with 8 ounces of water. Avoid grapefruit juice during budesonide treatment.

Budesonide for the treatment of mildly to moderately active Crohn's disease: Adults: 9 mg daily for up to 8 weeks; repeat 8-week course of treatment with recurrent episodes of active disease. Pediatrics 8 to 17 years weighing more than 25 kg: 9 mg once daily for up to 8 weeks, then 6 mg once daily for 2 weeks.

To maintain clinical remission in mild to moderate Crohn's disease: Adults: 6 mg daily for up to 3 months; discontinue 3 months after completion of tapering. Continuation of treatment beyond 3 months has not been shown to provide substantial clinical benefit. When switching from oral prednisolone, begin tapering the prednisolone dose and simultaneously initiate ENTOCORT EC.

Hepatic Impairment: Consider reducing dosage to 3 mg once daily in adult patients with moderate hepatic impairment (Child-Pugh Class B). Dosage Form and Strength Extended Release Capsules: 3 mg.

Medical Companion Travel is an overseas medical service company. For more information about budesonide, patients can consult the Medical Companion Travel Service.