罗氟司特可以治疗哮喘吗？罗氟司特药理作用及机制

The drug that has been approved for the treatment of chronic obstructive pulmonary disease is a new, highly selective phosphodiesterase 4 inhibitor and a new COPD treatment drug. So, can roflumilast treat asthma? What are the pharmacological effects and mechanisms of roflumilast?

The field of treating asthma with roflumilast is still in the exploratory stage. Clinical trials have shown that roflumilast can effectively improve asthma control, inhibit asthma-related inflammatory indicators, and improve lung function. Roflumilast can antagonize the immediate-phase asthmatic response and delayed-phase asthmatic reaction induced by allergen challenge. Roflumilast can reduce the rate of asthma exacerbations and prolong the time to first acute exacerbation after treatment. Roflumilast can reduce patients' long-term risk of asthma attacks.

Good safety and tolerability are the characteristics of roflumilast, and it has broad prospects in the treatment of asthma. As a highly selective PDE4 inhibitor, roflumilast has the ability to improve airway remodeling and anti-inflammatory effects. Roflumilast is mainly expressed on inflammatory cells related to asthma, including eosinophils, neutrophils and mast cells. Moreover, this drug can also relieve asthma symptoms and reduce the use of relieving drugs. Roflumilast can effectively improve lung function, reduce the number of acute asthma attacks, and prolong the duration of acute attacks. The therapeutic effect is very good.

Roflumilast can treat asthma. The drug can specifically act on a certain enzyme Chemicalbook involved in smooth muscle contraction, preventing the degradation of cAMP, thus blocking the transmission of pro-inflammatory response signals. Roflumilast has achieved good results in the clinical treatment of asthma and chronic obstructive pulmonary disease.

Roflumilast, which was first approved for marketing in the United States, was developed by Altana Pharma. However, there is currently no domestic information showing the launch of roflumilast. In other words, patients’ friends cannot buy roflumilast in hospital pharmacies. At this time, patients can choose overseas medical service organizations such as Medical Travel to obtain roflumilast. They can buy genuine drugs directly mailed by the manufacturer without going abroad. It is cost-effective and has many versions, which also reduces a lot of financial burden.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

Recommended related articles: