罗氟司特在哪能买到？

Roflumilast is a phosphodiesterase IV inhibitor that was first approved by the EMA in 2010 as an add-on therapy to the treatment of bronchiectasis for the maintenance treatment of severe COPD in adult patients with chronic bronchitis who have a history of frequent exacerbations. In Europe, roflumilast has multiple trade names, including Daxas, Libertek and Daliresp. It was first launched in Germany in 2010 and soon afterwards in the UK. After supplementing relevant information and data analysis as required by the FDA, it was approved by the FDA in March 2011 and launched in the United States in June of that year.

Roflumilast is a phosphodiesterase 4 (PDE-4) inhibitor. It mainly reduces the production of PDE-4 and inhibits the degradation process of cyclic adenosine monophosphate (cAMP), leading to an increase in cAMP levels, thereby inhibiting the release of inflammatory factors and mediators such as mast cells and monocytes, achieving anti-inflammatory effects; in addition, it can also reduce a variety of macrophage chemokines, including eosinophil chemoattractant 2 (CCL2), CCL3, CCL4 and interferon gamma-induced protein 10 ( The release of CXCL10) and tumor necrosis factor α (TNF-α) inhibits the chemotaxis and migration activity of neutrophils, and finally promotes cell apoptosis. Some studies believe that roflumilast can improve lung function and reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD).

Where can I buy it? Currently, roflumilast is not marketed in China and is not eligible for medical insurance. In other words, if patients want to purchase the drug, they must go abroad to purchase it. Traveling abroad to buy medicines is a long journey and requires a lot of manpower and material resources. Coupled with the huge medical expenses, many patient families are overwhelmed. However, according to Medical Companion Travel, 500μg*90 tablets of roflumilast costs approximately $2,850 per box. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. If you want to buy roflumilast but don’t want to go abroad, you can contact domestic overseas medical institutions (Medical Travel) to help you buy the drug. For more information about roflumilast, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.