How to treat adverse reactions caused by tobramycin inhalation solution?

Introduction: Tobramycin inhalation solution contains tobramycin, an aminoglycoside antibiotic from Streptomyces dwarfism, used to treat various types of bacterial infections. Compared with traditional systemic administration, tobramycin inhalation solution can directly act on the diseased parts of the lungs and increase the local drug concentration through inhalation administration, thus exerting a better antibacterial effect. At the same time, local administration reduces the distribution of drugs throughout the body and reduces the risk of systemic toxic reactions.

Adverse reactions of tobramycin inhalation solution

1. Ear and labyrinth diseases: It is ototoxic. Long-term or excessive use may cause damage to the vestibular nerve and cochlear nerve, thereby causing hearing loss and tinnitus.

2. Skin and subcutaneous tissue diseases: Tobramycin may cause allergic reactions, which may be manifested as allergy, itching, urticaria, and rash.

3. Nervous system diseases: Tobramycin inhalation solution may have certain effects on the nervous system, and patients may suffer from voice loss and taste disorders.

4. Respiratory system, chest and mediastinal diseases: Tobramycin inhalation solution may cause bronchospasm, cough, wheezing and oropharyngeal pain.

5. Metabolic and nutritional diseases: Decreased appetite may be a manifestation of the side effects of tobramycin inhalation solution.

Measures for dealing with adverse reactions of tobramycin inhalation solution

1. Ototoxicity: Tobramycin inhalation solution has potential ototoxicity and may cause hearing loss or tinnitus. If these symptoms occur, you should contact your doctor immediately and consider adjusting your dose or switching to another medication.

2. Respiratory problems: Tobramycin inhalation solution may cause coughing, wheezing or difficulty breathing. If symptoms are severe, use should be suspended and seek medical help.

4. Oral and throat irritation: This can be relieved by drinking more water or using a mild mouthwash.

5. Allergic reaction: If allergic symptoms occur, the drug should be stopped immediately and anti-allergic treatment should be carried out under the guidance of a doctor.

6. Local skin reaction: It can be improved by using anti-allergic drugs or topical corticosteroid ointment under the guidance of a doctor.

When dealing with it, the most important thing is to communicate with the doctor in time and adjust the treatment plan according to the doctor's advice. In the meantime, patients should pay close attention to their body's reactions and seek immediate medical help if they experience any discomfort.