普乐可复有什么不良反应,疗效怎么样?
The immunosuppressive effect of Proclofor is tens to hundreds of times that of cyclosporine in both in vitro and in vivo tests. It can be used to prevent graft rejection after liver or kidney transplantation. It can also be used to treat graft rejection that cannot be controlled by other immunosuppressive drugs after transplantation. So, what are the adverse reactions and what is the efficacy?
adverse reactions
Including high blood pressure, tremor, headache, hypercalcemia, hyperglycemia, hypophosphatemia, insomnia, sensory disturbance, visual disorders (such as cataracts, amblyopia), renal function abnormalities (such as increased blood creatinine, increase or decrease in urea nitrogen and urine output), constipation, diarrhea, nausea, leukocyte hyperplasia, etc. In addition, autoimmune diseases, allergic reactions, infections, etc. are side effects that may occur with Plexif. Patients have different physiques and conditions, and the manifestations of side effects are also different. For more details, please refer to the drug instructions.
Therapeutic effect
The efficacy of Proclofor is still very significant. Proclofor is a highly immunosuppressive drug that can inhibit the production of cytotoxic lymphocytes that are the main cause of transplant rejection, inhibit the activation of T cells and the proliferation of T helper cell-dependent B cells, thereby exerting its medicinal effect. Preclosumab is expected to reduce acute and chronic rejection in liver and kidney transplant recipients. However, in the previous cyclosporine-based immunosuppressive regimen, the problem of irreversible chronic rejection remains the same. Although increasing the dose will have further effects, it will bring serious adverse reactions.
Proclofor can reduce the original treatment cost by 1/3 to 1/2 (because patients using this product can be discharged from the hospital 2 weeks after surgery, while those using cyclosporine need 4 weeks). At the same time, adverse reactions are also significantly reduced. It has the advantages of low mortality, good transplant success rate, high transplant survival rate, and relative independence from steroids. The above is the content of the adverse reactions and treatment effects of Pulecofu, I hope it can help you!
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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