孤儿药:解腺瘤片不良反应和警告注意事项

The adenoma solution is mainly used for inoperable, functional and non-functional adrenocortical cancer, adrenal hyperplasia and tumor-induced hypercortisolism. It is currently the only drug approved for adrenocortical cancer. Existing data indicate that adenoma tablets not only modulate steroid metabolism in peripheral tissues but also directly inhibit the adrenal cortex. Today let’s learn about the adverse reactions and warnings of the orphan drug: Jieadenomas Tablets.

The most common side effects of adenoma tablets include: depression of the central nervous system, dizziness, drowsiness, skin rash, loss of appetite, nausea, vomiting, diarrhea, etc.

Other side effects of JieAdenoma Tablets: headache, high blood pressure, orthostatic hypotension, depression, confusion, muscle tremors, hemorrhagic cystitis, etc.

If patients with adrenal mesothelial cancer experience the above-mentioned adverse reactions while taking the Adenoma Solution, the patient should receive treatment as soon as possible. If necessary, he or she needs to contact the doctor for dose adjustment or discontinuation of the drug. However, this must be done under the professional guidance of a doctor. If the patient changes the dose of the drug without authorization, more serious complications may occur.

Precautions for adenoma removal tablets are as follows:

1. Adenoma Solution Tablets are chemotherapy drugs. Care must be taken when handling and discarding the drugs.

2. Taking Adenoma Jie Tablets on a full stomach can increase absorption.

3. Adenoma Jie tablets can suppress the central nervous system and cause drowsiness, dizziness, etc. Therefore, while taking the medicine, try to avoid driving or operating machinery and other activities that require a high degree of mental concentration.

4. If patients taking the medicine develop infection, trauma or other diseases, they should seek medical treatment immediately to avoid acute adrenocortical insufficiency.

5. Patients with severe side effects may experience adrenal cortex atrophy and necrosis. To avoid adrenal insufficiency during medication, glucocorticoids may be supplemented appropriately.

Adenoma tablets were approved by the U.S. Food and Drug Administration (FDA) in 1970 for the treatment of adrenocortical cancer. Subsequently, mitotane tablets were approved for marketing in Canada (1978), Brazil (1988), Hong Kong, China (1989), South Korea (2001) and other countries and regions, and was listed as an orphan drug by the European Medicines Agency (EMA) in 2002. Currently, the French company Laboratoire HRA is the only global manufacturer of mitotane tablets with a license.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.