2025-10-19 11:44:20
Sotorasib, a specific inhibitor of oral KRAS G12C launched by Amgen in the United States, was approved for marketing for the first time under the accelerated channel of the US FDA on May 28, 2021. It was first used to treat patients with KRAS Patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with G12C mutations mark the advent of oral targeted therapy for KRAS-mutated lung cancer.